WPEN

WPEN may refer to:


 * WPEN (FM), a radio station (97.5 FM) licensed to Burlington, New Jersey
 * WKDN (AM), a radio station (950 AM) licensed to Philadelphia, Pennsylvania (formerly WPEN, 1929-2012)
 * WMGK, a radio station (102.9 FM) licensed to Philadelphia, Pennsylvania (formerly WPEN-FM, 1947-1975)
 * WCAU, a television station (channel 10) licensed to Philadelphia, Pennsylvania (formerly WPEN-TV, 1946-1947)
 * WOGL, a radio station (98.1 FM) licensed to Philadelphia, Pennsylvania (formerly WPEN-FM, 1943-1947)
 * WPEN-LP, a defunct television station in Hampton, Virginia