WRU

WRU may refer to:


 * Welsh Rugby Union, sports association in Wales
 * Waikato Rugby Union, sports association in Waikato, New Zealand
 * Wesleyan Reform Union, Methodist church group in Britain
 * WRU, station code for West Ruislip station, Hillingdon, Greater London, UK
 * Western Reserve University, now part of Case Western Reserve University in Cleveland, Ohio