Wayne High School

Wayne High School can refer to:


 * Wayne High School (Indiana) in Fort Wayne, Indiana
 * Wayne High School (Nebraska) in Wayne, Nebraska
 * Wayne High School (New York) in Ontario Center, New York
 * Wayne High School (Ohio) in Huber Heights, Ohio
 * Wayne High School (West Virginia) in Wayne, West Virginia
 * Wayne High School (Utah) in Bicknell, Utah
 * Wayne County High School (Georgia) in Jesup, Georgia
 * Wayne County High School (Kentucky) in Monticello, Kentucky
 * Wayne County High School (Mississippi) in Waynesboro, Mississippi
 * Wayne Memorial High School in Wayne, Michigan