Wesson

Wesson may refer to
 * Wesson, Mississippi, a town in Copiah County
 * Wesson, Texas, a ghost town in Cormal County
 * Wesson, Arkansas, a township in Union County, Arkansas
 * Wesson cooking oil, a brand now owned by Richardson International, Limited
 * USS Wesson (DE-184), a United States Navy destroyer escort
 * Wesson (surname)