West 21st Street Historic District

West 21st Street Historic District is a national historic district located at Erie, Erie County, Pennsylvania. It includes 35 contributing middle and upper class residential buildings built between 1857 and 1939. They are in a variety of popular architectural styles including Queen Anne, Italianate, and Colonial Revival. Many of the buildings have been converted to multi-family use.

It was added to the National Register of Historic Places in 1990.