Wikipedia:Articles for deletion/Autosomal chromosome epigenetic silencing to cure Down syndrome


 * The following discussion is an archived debate of the proposed deletion of the article below. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review).  No further edits should be made to this page.

The result was Delete: thorough attempts to find reliable secondary sources per MEDRS have failed. RockMagnetist (talk) 15:34, 18 May 2014 (UTC)

Autosomal chromosome epigenetic silencing to cure Down syndrome

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A case study of a result in one paper. The last section might be better to be put in a paragraph of Down syndrome rather than an individual article. Mys_721tx (talk) 08:01, 6 May 2014 (UTC)
 * Note: This debate has been included in the list of Medicine-related deletion discussions. • Gene93k (talk) 23:03, 7 May 2014 (UTC)
 * Note: This debate has been included in the list of Science-related deletion discussions. • Gene93k (talk) 23:03, 7 May 2014 (UTC)


 * Delete?. Looks like original synthesis. Too early. Xxanthippe (talk) 23:53, 7 May 2014 (UTC).
 * Delete Some info can maybe be merged into Trisomy 21, but that is just a single (even if remarkable) study. -- cyclopia speak! 15:08, 8 May 2014 (UTC)
 * Merge Merge subsection, Autosomal Silencing with XIST, into page on Down syndrome research — Preceding unsigned comment added by Tenderboutons (talk • contribs) 18:46, 9 May 2014 (UTC)
 * Relisted to generate a more thorough discussion so a clearer consensus may be reached.


 * Please add new comments below this notice. Thanks, NorthAmerica1000 01:07, 14 May 2014 (UTC)


 * Delete The current article lacks secondary sources to support the material that are recommended by WP:MEDRS; this is synthesis of several primary sources, with heavy reliance on a single August 2013 study in Nature. It's a very important, groundbreaking study, but is preliminary, foundational research that probes what it refers to as "the major first step towards potential development of 'chromosome therapy'". Merging elsewhere is inappropriate; medical topics are treated differently than other subjects on Wikipedia, and coverage of proposed medical cures should generally be referenced with secondary sources, not individual studies (primary sources). Rationale and details for the different treatment are discussed in WP:MEDRS and its Talk page archives. If secondary sources can be found with substantial information on this approach, it may warrant an article, but I didn't find any; the Nature article is recent, and while it has been widely cited in medical literature, it does not seem to have been cited in any reviews yet. (Note: I'm a layperson with no medical expertise; weigh my opinion accordingly). Agyle (talk) 19:52, 17 May 2014 (UTC)
 * The above discussion is preserved as an archive of the debate. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review). No further edits should be made to this page.