Wikipedia:Articles for deletion/Gluten exorphine


 * The following discussion is an archived debate of the proposed deletion of the article below. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review).  No further edits should be made to this page.  

The result was Keep and rename --Bubba hotep 20:52, 6 April 2007 (UTC)

Gluten exorphine

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I was trying to find sources for this and no results came up on PubMed. Did a Google search and found only one none-Wikipedia clone site featuring this term. I suspect it's a hoax. Article has been around since 2005. Oldak Quill 03:33, 1 April 2007 (UTC)
 * Weak Delete while this site suggests its a real term, I don't know how verifiable the info in the article is. Mr.Z-man  talk ¢ Review! 03:54, 1 April 2007 (UTC)
 * Rename per Collabi below. Mr.Z-man  talk ¢ Review! 21:01, 4 April 2007 (UTC)
 * Delete. No sources whatsoever, can't be verified, looks like something sold on late-night cable TV. Realkyhick 23:47, 1 April 2007 (UTC)

Did a quick check on Pub Med and came up with the following refs and links to abstracts: "Delta opioid peptides derived from plant proteins. (Yoshikawa M, Takahashi M, Yang S, Curr Pharm Des. 2003;9(16):1325-30.)", "Behavioral and pharmacological studies on gluten exorphin A5, a newly isolated bioactive food protein fragment, in mice. (Takahashi M, Fukunaga H, Kaneto H, Fukudome S, Yoshikawa M., Jpn J Pharmacol. 2000 Nov;84(3):259-65.)", [http://http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=8422933&query_hl=1&itool=pubmed_docsum "Gluten exorphin C. A novel opioid peptide derived from wheat gluten. (Fukudome S, Yoshikawa M, FEBS Lett. 1993 Jan 18;316(1):17-9.)"], and [http://http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=1309704&query_hl=1&itool=pubmed_docsum "Opioid peptides derived from wheat gluten: their isolation and characterization. (Fukudome S, Yoshikawa M, FEBS Lett. 1992 Jan 13;296(1):107-11.)"]. Good catch by Collabi. Looks like someone was trying to do a British spelling of "exorphin". Teach me to be too quick about yelling Delete! Esseh 19:10, 3 April 2007 (UTC)
 * Delete. Reason for gluten intolerance given by The Penguin Dictionary of Biology (10th ed., M. Thain & M. Hickman, Penguin, 2000) is an allergic reaction, leading to coeliac disease and subsequent malabsorption of nutrients (i.e. starvation with a full belly). In scanning Mr.Z-man's linkEsseh 09:31, 3 April 2007 (UTC), they describe the symptoms of starvation (weakness, neuropathy, headaches...) combined with an excess of unabsorbed food in the GI tract and colon irritation (flatulence, diarrhea). Purple ergot of rye, some mushrooms, toads, and bad fugu may cause halucinations, but gluten? Naw, this is a hoax, though perpetrated by someone with at least a minimal knowledge of oligopeptide structure . Esseh 09:31, 3 April 2007 (UTC)


 * Strong Keep! Article's title is mispelled. Do a paper search on "Exorphin" -- no trailing E -- and you will find dozens of papers on the topic from reputable institutions, which at least demonstrates that exorphines exist and are documented science. Too bad none of these citations are in the article. What I am less sure of is the conclusions at the top of the article -- a quick browse of the research didn't immediately turn up any empirical link to the diseases mentioned -- but the article should be cited and supported, not struck. Collabi 10:34, 3 April 2007 (UTC)
 * Comment: You appear to have some knowledge of the subject. Could you possibly do some work to fix this article? Realkyhick 17:09, 3 April 2007 (UTC)
 * I'm no molecular biologist, but I can try. Unfortunately I lack access to a university research library these days so I will be mostly trying to glean information from abstracts. Collabi 18:13, 3 April 2007 (UTC)
 * rename per collabi RogueNinja 18:39, 4 April 2007 (UTC)
 * Rename to Gluten exorphin. Nature seems to have at least one article on this, though they also called it an "exorphin" not "exorphine" .  Someguy1221 20:49, 4 April 2007 (UTC)
 * Rename per above.Biophys 02:34, 5 April 2007 (UTC)
 * Rename per above. Jerry 20:17, 6 April 2007 (UTC)
 * The above discussion is preserved as an archive of the debate. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review). No further edits should be made to this page.