Wikipedia:Articles for deletion/Reelin hypothesis of the development of schizophrenia


 * The following discussion is an archived debate of the proposed deletion of the article below. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review).  No further edits should be made to this page.  

The result of the debate was delete. (ESkog)(Talk) 21:59, 6 June 2006 (UTC)

Reelin hypothesis of the development of schizophrenia
Original research. Google hits for "reelin hypothesis": 79. Google hits for '"reelin hypothesis" -answers.com -wikipedia -thefreedictionary -encyclopedian -websters-dictionary-online': 1, which is about autism, and wherein the phrase "reelin hypothesis" is split across a sentence boundary "...protein called reelin. Hypothesis about the involvement...". AFAICT, reelin is present in abnormal quantities in schizophrenics, but this article is 1,500 words long, and outside of the title the word "reelin" only appears twice. It seems to me to be a vehicle for the author's fringe views of the epidemiology of schizophrenia. — Preceding unsigned comment added by Moe Aboulkheir (talk • contribs)


 * Delete, unreferenced. The article admits that it's original research. Dr Zak 03:08, 29 May 2006 (UTC)
 * Delete non-notable, original research plus only 1 goggle result. Stormscape 03:14, 29 May 2006 (UTC)
 * Delete Unreferenced and even original research can be corrected in many cases but the entire article appears to be OR and it's a non notable hypothesis at that. Pegasus1138 Talk 03:17, 29 May 2006 (UTC)
 * Delete per above. --JChap 03:26, 29 May 2006 (UTC)
 * Merge relevant information to reelin, and delete the POV suppositions. There's certainly a topic here (see ), although it's not known under the name 'Reelin hypothesis'. Z iggurat 03:35, 29 May 2006 (UTC)


 * Delete Unsourced, original research. This article has been in existence since 2002 and has yet to take on a credible form.  However, there are 26,000 Google hits for the Reelin protein connection to schizophrenia so statements that it has only one Google hit are mistaken.  Still, beacause of the utter absence of references, there is nothing here that could plausibly used in the Reelin article.  Ande B 04:50, 29 May 2006 (UTC)
 * Question. Aren't there any usable references among these 26,000 Google hits? --Lambiam Talk 11:21, 29 May 2006 (UTC)
 * Reply There is technical information out there about the correlation between reelin levels and propensity toward schizophrenia but it has not apparently risen to the level of being an "hypothesis" as much as it is a speculation that warrants further investigation.  I would think that this information would best be covered within the schizophrenia article but WP should not be designating something as a "hypothesis" when the scince / medical community has not already done so.  ("Hypothesis" has a technical meaning within the scietific community.) I haven't done any research in this area, though, so you may come to a different conclusion if you sift through some of the materials out there.  Ande B 19:31, 29 May 2006 (UTC)


 * Delete a classic example of OR. Kevin 11:06, 29 May 2006 (UTC)
 * Delete, unsourced, original research. --Ter e nce Ong 14:31, 29 May 2006 (UTC)
 * Delete Unsourced, OR.  OhNo itsJamie Talk 22:04, 29 May 2006 (UTC)
 * Delete. An unreferenced, OR question and answer session the author had with themselves. Grand  master  ka  01:03, 30 May 2006 (UTC)


 * Delete. The article itself seems too strange. At first, i voted "merge", but I see nothing of much value to merge there. The article is way too "soupy". BTW. Yes, there are credible and duplicated scientific results showing that Reelin is low in the brains of SZ patients. I plan to include the data in the "Reelin" article (I explore the reelin/DAB1 cascade mechanisms and write two versions of "Reelin" article in parallel: in Russian and in English. For the Reelin's role in SZ, look out for Erminio Costa's scientific works, for example: http://www.pubmedcentral.gov/articlerender.fcgi?tool=pubmed&pubmedid=15961543 --CopperKettle 12:08, 30 May 2006 (UTC)
 * P.S O.K. (0: I've included references to the postmortem studies of the schiz. brains (proving the link to reelin deficiency) in the Reelin article. Comments are welcomed. My language may have stylistical mistakes (I'm Russian), so proof is welcomed too. --CopperKettle 13:29, 30 May 2006 (UTC)
 * Merge if there is anything of value anyone can extract from it, the article is poor, otherwise Delete. Talk of a reelin hypothesis is a little unusual but there is plenty of scientific basis for it (e.g. which says "the morbidity risk of schizophrenia...may arise as a consequence of compromised RELN expression" - essentially stating a reelin hypothesis of schizophrenia), but would be better covered as part of the neurodevelopmental hypothesis. --Coroebus 10:53, 1 June 2006 (UTC)


 * The above discussion is preserved as an archive of the debate. Please do not modify it. Subsequent comments should be made on the appropriate discussion page (such as the article's talk page or in a deletion review). No further edits should be made to this page.