Wikipedia:Featured article review/Lesch-Nyhan syndrome/archive1


 * The following is an archived discussion of a featured article review. Please do not modify it. Further comments should be made on the article's talk page or at Wikipedia talk:Featured article review). No further edits should be made to this page.

The article was removed 08:49, 10 June 2007.

Review commentary

 * Messages left at User talk:Larsie, Medicine and Medical Genetics. Sandy Georgia (Talk) 14:39, 6 May 2007 (UTC)

Lesch-Nyhan syndrome was promoted in December 2004, and does not meet current standards. The largest deficiency is 1c; most of the article is uncited. It also fails 1b, comprehensive; per WP:MEDMOS the Prognosis, Prevention or Screening, Epidemiology and History sections are underdeveloped. There is an entire section on "Oxidative stress" which needs to be reviewed and incorporated into the correct place in the article structure, if worthy of keeping. There are minor 2 (WP:MOS) issues, which can easily be fixed if the article is cited and completed. Attention to wikilinking is needed. The article may be outdated; a review of the current literature is in order. Sandy Georgia (Talk) 14:36, 6 May 2007 (UTC)

Leave the oxidative stress bit in. While first suggested to play a role in LNS, the prooxidative propeties of urate have been getting quite a bit of play recently with respect to Lesch-Nyhan syndrome, metabolic syndrome, atherosclerosis, and stroke ( e.g., Elevated Uric Acid and Ischemic Stroke: Accumulating Evidence That It Is Injurious and Not Neuroprotective.   Likewise,  always admitting the possibility of improvement, at first glance,  the cites seem pretty up-to-date.  Remember, this is a rare disease and sometimes not a lot of papers show on such.Pproctor 17:30, 22 May 2007 (UTC)
 * Oxidative stress

FARC commentary

 * Suggested FA criteria concerns are citations (1c), comprehensiveness (1b), and MoS issues (2). Marskell 15:14, 21 May 2007 (UTC)


 * Remove, nothing happening, article fails 1c (mostly uncited), and 1b (per suggested sections at WP:MEDMOS). Also, questions of original research in oxidative stress material.  Sandy Georgia  (Talk) 05:47, 28 May 2007 (UTC)
 * Remove per 1c (my fault for nominating Schizophrenia for FAR soon after this FAR got underway, which kept Sandy tied up a little). LuciferMorgan 22:10, 28 May 2007 (UTC)
 * The above discussion is preserved as an archive. Please do not modify it. Subsequent comments should be made on the article's talk page or in Wikipedia talk:Featured article review. No further edits should be made to this page.