Wikipedia:Ioannidis

The most cited paper in the history of the Public Library of Science is the 2005 paper by John P. A. Ioannidis, Why Most Published Research Findings Are False

Early studies in petri dishes or rodents are the stuff of tabloid headlines, not encyclopaedias.

If a claim comes from a single preliminary study, it probably should not be included unless there is substantial independent commentary in the scientific literature. Because it's probably wrong. And that's why no competent Wikipedian would make significant claims for human effects based on early animal or in vitro studies.