Wikipedia:Today's featured article/requests/Enzyme inhibitor

Enzyme inhibitor

 * This is the archived discussion of the TFAR nomination for the article below. Subsequent comments should be made on the appropriate discussion page (such as Wikipedia talk:Today's featured article/requests). Please do not modify this page.

The result was: scheduled for Today's featured article/March 28, 2023 by Wehwalt (talk) 13:56, 9 February 2023 (UTC)



An enzyme inhibitor is a molecule that binds to an enzyme's active site, or another site on the enzyme, and blocks the enzyme's catalysis of the reaction. Enzyme inhibitors are generally specific to one enzyme and control that enzyme's activity. They also control essential enzymes such as proteases or nucleases that, if left unchecked, may damage a cell. Many poisons produced by animals or plants are enzyme inhibitors, and many drug molecules are enzyme inhibitors that inhibit an aberrant human enzyme or an enzyme critical for the survival of a pathogen. Since anti-pathogen inhibitors generally target only one enzyme, such drugs are highly specific and generally produce few side effects in humans. Medicinal enzyme inhibitors often have low dissociation constants, meaning a minute amount of the inhibitor will inhibit the enzyme. The discovery and refinement of enzyme inhibitors are researched in biochemistry and pharmacology.
 * Most recent similar article(s): Rotavirus in Sept 2022, in the sense that both are really small? Not that much coverage on this topic.
 * Main editors: FAC nom,  FASA recipient.
 * Promoted: Sept 20, 2006. FAR Aug 6, 2022.
 * Reasons for nomination: I want to highlight older articles that are ready for main page to the co-ords, and give time for subject-matter experts to improve upon the blurb. This would be a TFA re-run from 2006.
 * Support as nominator. Z1720 (talk) 03:58, 9 February 2023 (UTC)