Wikipedia:USEP/Courses/JHU MolBio Ogg FA13/Group 81G

Group 81G
This is a group page for the Johns Hopkins Molecular Biology course. This group will be working on the article TBD.

Use the talk page here to collaborate as a group, when learning to use and navigate Wikipedia, assessing articles, or for any other topic.

Use this page (not the talk page) for article assessments; rationale for selecting an article; etc (as specified in the milestone summary chart.

Please create a new section here for each of those assignments.

Initial article assessments from KevinBrownJHU
Complementarity This article is a bit short and could use some added information related to complementarity. Maybe add information related to what it can help with, such as transcript regulation caused by Antisense Transcripts or even in the presence of kissing hairpins. The page seems to be started about how things line up, but light on a lot of real details. Such as the fact that A pairs with T, but there are plenty of cases where it isn't always so, such as in extremophiles.

Neutral Mutation This stub of an article needs to be expanded on to include more details of how and why some mutations are silent. SNPs show this to some degree as does the standard codon table for translation. SNPs are also part of population studies, that this stub links to. Not sure if this fits with the main stub about neutral mutations, but the conversion of one pathway to another via mutation would seem to fit as a neutral change. A study was done on mtDNA with gene variants to determine if the variants were just polymorphisms or deleterious to a human

Extrachromosomal DNA

 * The article Extrachromosomal DNA is a stub. It contains no citations or other references, is very short (two short paragraphs), contains a brief definition and has minimal information covering the occurrence of extra chromosomal DNA, "normal" vs. cancerous. The talk page contains no discussion but shows that the article is part of two WikiProjects:


 * WikiProject_Molecular_and_Cellular_Biology, which classifies the article as a stub and as highly important
 * WikiProject_Genetics which hasn't accessed the article yet.

Histone octamer

 * The article Histone octamer is a stub. The article consists of a single paragraph giving a very brief definition and listing the sub units of the histone octamer. It contains no citation or inline references, but merely redirects the reader to a few other wiki articles  Nucleosome, Histone and Chromatin, respectively. The talk page is very limited as it has only one user comment. The article is also accessed by the WikiProject_Molecular_and_Cellular_Biology, which classifies it as a stub and as highly important.

Article selection rationale
Complementarity is a good choice as the current information is barely past the level of a stub article. A lot of new information and organization will be needed as the article as it currently exists seems to contain information already present in the base pair section. Some possible expansions include self-complementary sequences (like the folding of RNA strands into functional units of tRNA). While the current article limits itself to just touching on DNA complementarity, amino acids also show a form of complementarity which leads to how a protein folds or how they bind to each other. Another Wiki-article, which may overlap with Complementary is Complementary DNA. It will be important to refer to the other Wiki article to avoid information overlap or in alternative to merge the articles if possible to ease user access. The article complementary was also assessed by the WikiProject_Molecular_and_Cellular_Biology. It classified the article as a stub and as highly important. Another reason for selecting the article is that nobody appears to be working on it. One of the few edits to the talk page was made in 2010 when information on tRNA and wobble were removed. It also appears as if in 2005 parts of the article were removed to create new sub article - leaving the "bare bones" without editing the main article.

Unit 8 progress report

 * Contributions consisted mainly of prose
 * Created table to visualize base pairing

Unit 10 progress report

 * Reviewed and implemented several suggestions from peer review
 * Added context to the lead section as well as links
 * Added prose to individual sections
 * Updated table on base pairing

Unit 12 progress report

 * Added more citations throughout article
 * Added more visuals
 * Added some prose such as cDNA
 * Improved language to make text more accessible

Unit 14 Final progress report

 * Revised wording throughout article based on suggestions
 * Edited overall article flow following  JFitz1974's advise
 * Added illustration and citation in Ambigrams section
 * Edited for typos throughout
 * Added prose such as a definition of Antisense transcript (suggested by Klortho)
 * Added brief introduction to the regulatory section (suggested by Donbinincom)
 * Added more visuals