Wikipedia:United States Education Program/Courses/JHU MolBio Ogg 2013/Group 81G

Group 81G
This is the Wikipedia page for 410.602 Molecular Biology, Spring, 2013, group 81G. This group will be working on the article Lysogenic cycle.

Use the talk page here to collaborate as a group, when learning to use and navigate Wikipedia, assessing articles, or for any other topic.

Use this page (not the talk page) for article assessments; rationale for selecting an article; etc.

Please create a new section here for each of those assignments.

Assessment of Genotyping

 * This article is very incomplete. It lists the ways of genotyping, but does not explain any of them or point out their strengths/weaknesses.  In addition, there are only 2 references cited. Jbmcgregor (talk) 01:19, 4 March 2013 (UTC)

Assessment of RNA of unknown function

 * The description of this topic is very brief. There are three cited examples given with a total of 4 references, but the description and explanation of their significance is weak and minimal. Jbmcgregor (talk) 01:23, 4 March 2013 (UTC)

Polymerase
The writing of this article is not as clear as it could be. It also appears to lack citations entirely so while it does not have original research, the article is not verifiable. The writing is neutral and has a picture of Taq polymerase but be more broad. Perhaps there could be mention of how polymerase activity can be modulated?


 * 1) http://books.google.com/books?id=8JTkGVC0UjkC&pg=PA39&dq=polymerase+taq&hl=en&sa=X&ei=KHEuUdXgGrOFyQHJyoDwAw&ved=0CDMQ6wEwAg#v=onepage&q=polymerase%20taq&f=false
 * 2) http://books.google.com/books?id=eoAKJpqcRFYC&pg=PA72&dq=polymerase+taq&hl=en&sa=X&ei=KHEuUdXgGrOFyQHJyoDwAw&ved=0CDgQ6wEwAw#v=onepage&q=polymerase%20taq&f=false
 * 3) http://books.google.com/books?id=Ju8XeJL9Fc4C&pg=PA157&dq=polymerase+taq&hl=en&sa=X&ei=KHEuUdXgGrOFyQHJyoDwAw&ved=0CDwQ6wEwBA#v=onepage&q=polymerase%20taq&f=false

Enhancer (genetics)
This article lacks several citations but appears to be written in a neutral manner and does not appear to have copyright violations. The article is also quite broad with its discussion of examples in the human genome and developmental evolution. 1. http://www.nature.com/nature/journal/v471/n7337/abs/nature09774.html 2. http://www.nature.com/nature/journal/v471/n7337/abs/nature09774.html

Bmesido1 (talk) 20:54, 27 February 2013 (UTC)

Hi Jen,

I had previously had this in the "Talk" section of our group page. I had read "create a new section" in the instructions to be literally create a new section. Just in case, here it is as well. I will look over the two you discussed and revisit others from the list for the group project. Hope you have been well.

Beatrice Bmesido1 (talk) 02:20, 5 March 2013 (UTC)

Article selection rationale
Our group chose Lysogenic cycle due to its importance, its interest to the members, and the plethora of information available to be contributed via secondary resources.

Currently, this article is rated as "high-importance" for both the WikipediaProject Viruses and the WikipediaProject Molecular and Cell Biology. There is also a lot of room for improvement as it is a stub article. The graphic provided is minimal and the article has few citations. While the article does not contain original research, there are sections that are not verifiable. There are also areas of the article that can be edited for clarity. In addition, there is an image used to illustrate the difference between the lytic and lysogenic cycles, but there is little explanation of the image.

In terms of secondary resources, our class's textbook Molecular Biology of the Gene by Watson et al. and Biology of Microorganisms (Twelfth edition) by Madigan et al. have relevant information that can be added to expand the breadth of the article.

For example, there is no mention of what happens when a virus undergoes a mutation that prevents it from leaving the host genome (cryptic virus). The article mentions bacteriaphage lamda but perhaps it can be rewritten to emphasize bacteriaphage lambda's importance as a model and what it tells us. For example, study of bacteriaphage lambda shows us a lysogenic virus determines lysis or lysogeny. The cI protein and the Cro repressor are important elements for this control.

One final part of the current page that could use additional work is the section where examples of different bacteria and virulence factors are mentioned. It is very brief as it is and it is an interesting topic that seems as if it may become a bigger topic in future research.