Wikipedia:WikiProject Molecular Biology/Molecular and Cell Biology/Help

Translation support for Osmoregulation related graphics required
Hi everyone, de:Benutzer:Biezl from de.WP has created two images depicting the issue of osmoregulation in freshwater and marine fishes which would perfectly fit into article Osmoregulation. As English is not our mother tongue we would appreciate to have the english wording/spelling checked prior to adding these images:
 * Image:Osmoseragulation Carangoides bartholomaei bw en.png
 * Image:Bachforelle osmoregulatoin bw en.png

If you have any remarks/proposals for a better wording, please answer directly on User Biezl's talk page. Regards, --Drahkrub (talk) 16:18, 20 December 2008 (UTC)


 * Done, improved versions:


 * Image:Osmoseragulation Carangoides bartholomaei bw en2.png
 * Image:Bachforelle osmoregulatoin bw en2.png

Smartse (talk) 15:51, 15 April 2009 (UTC)
 * Cool - I see that you added the images already to the article. Thx a lot. --Burkhard (talk) 22:11, 15 April 2009 (UTC)

Devyn Smith
Someone associated with the Frankel Group has created a spate of WP:COI articles, including one on Devyn Smith who may be a notable stem cell researcher. Does anyone here have the time to check the refs? Shawn in Montreal (talk) 17:52, 16 February 2009 (UTC)


 * See Articles for deletion/Devyn Smith. Tim Vickers (talk) 18:14, 16 February 2009 (UTC)

Small problem at ELISA
Hi everyone,

Gcarotsans (talk) pointed out a possible problem with the ELISA page, section Indirect ELISA; see talk. Just thought I'd mention it here to catch the eye of an expert. Adrian J. Hunter(talk•contribs) 12:12, 3 March 2009 (UTC)

Sulfation need attention
Sulfation page seems in need of splitting into several articles; I'm no specialist, so if any biochem expert is willing to look at it, it would be great. Cheers, -- C opper K ettle  12:41, 22 May 2009 (UTC)

Photosynthesis lead section
Because of my lack of the english language I can't rewrite the lead section of photosynthesis by myself, so I need some help of other guys. As written in Lead section: "In general, specialized terminology should be avoided in an introduction. " Terms as organic compounds, Archaea, source of Carbon, might not be really specialized terms but rather simple biology terms, but many people who will try to read this introduction just want to know what photosynthesis basically is and how it affects our life every day. So I think that these sentences: "Photosynthetic organisms are called photoautotrophs, since it allows them to create their own food. However, not all organisms that use light as a source of energy carry out photosynthesis, since photoheterotrophs use organic compounds, rather than carbon dioxide, as a source of carbon." ... should be changed to some proper information about: autotrophs, heterotrophs and how photosynthetic organisms are fundemental to the food chain and atmosphere in ecosystems. It might be also good to explain the difference between the terms inorganic and organic compounds. Kasper90 (talk) 08:46, 27 May 2009 (UTC)

RuBisCO
The RuBisCO article has accumulated a large number of edits apparently by someone called Hadi Farazdaghi. Many of the edits cite the personal website of Hadi Farazdaghi, which seems to have a collection of self-published articles. If you can help sort this out please see Talk:RuBisCO. --JWSchmidt (talk) 04:26, 14 June 2009 (UTC)

In response to JWSchmidt I have three comments: 1) I have used the reference to my site for further discussion and clarification of the subject. 2) A more detailed discussion of Rubisco reaction is provided in chapter of a new book by Springer that I have referenced to (Farazdaghi 2009). 3) As I have discussed on the site, the model of Farquhar, von Caemmerer and Berry which has been dominantly used for the last thirty years is based on a mathematical mistake in which the velocity of reaction is equated with the efficiency of reaction at low CO2 concentration levels (see the abstract of von Caemmerer and Farquhar 1981, referenced in the text). The latest article by Sharkey et al (2007, Plant Cell & Environment 30:1035-1040)has added additional problems which are also discussed in Farazdaghi (2009). Further discussion by interested parties on the author's site is welcome.

Hadi Farazdaghi

Fluorescence in the life sciences and copyright
Upset about the mess and lenght of the paragraph for fluorescence in life science in the fluorescence article, I have copied it and expanded it into a new page fluorescence in the life sciences, (a valid policy see Splitting).

My doubt: A lot of dyes are owned by invitrogen (they own the market), so do I pretend copyright does not matter or add (R) symbol or similar? If I do the latter options, jit is quite likely that someone may think I work for them and messes up the article... — Preceding unsigned comment added by Squidonius (talk • contribs)
 * According to Manual of Style (trademarks), ™ and ® should generally not be used in Wikipedia for trademarks. Celefin (talk) 16:54, 15 July 2009 (UTC)

WP:JOURNALS need helps!
I've noticed that most of the most popular missing journals are biology related. Help would be appreciated to turn that see of red into a sea of blue. Most of these seem to be abbreviations that should be redirected to the main journal. Thanks. Headbomb {{{sup|ταλκ}}κοντριβς – WP Physics} 05:30, 27 July 2009 (UTC)

Bad code on NFIL3 page?
Could somebody check the code on the NFIL3 page, preferably with Firefox 3.5.3?

I searched for E4BP4 using Firefox 3.5.3, but I couldn't get to the page. Instead of opening the page, Firefox stalled, Windows Task Manager told me CPU usage was up to 100%, Firefox finally froze, and I had to end Firefox with Windows Task Manager.

Same thing happened when I searched for NFIL3.

I tried again in Internet Explorer, and it worked fine.

I went back to Firefox again, tried searching other WP pages, and the other pages worked fine.

So I suspect there may be some funny code on the NFIL3 page that freezes at least some configurations of Firefox 3.5.3.

(E4BP4 was just mentioned on Slashdot.) --Nbauman (talk) 20:04, 14 September 2009 (UTC)


 * P.S. Now it's working OK. When you bring your car to the mechanic, the problem stops. Maybe you should forget about it unless somebody else has this problem. --Nbauman (talk) 20:08, 14 September 2009 (UTC)

I am writing for a HIV positive person for 22 years. He is currently living in Arizona and is having problems getting medication. This is really important to him and he is open to help or suggestions. Thanks.

Articles with confused content to clean-up
Heya, I've been going through a lot of pages relating to protein domains lately and there's a few sets of interrelated pages where the subject matters have become confused. The ones which I'm currently looking into are: If anyone fancies helping out with tidying these pages up, that would be awesome! ((PS, i hope i've put this on the right page :s)) Ta, Abergabe (talk) 15:23, 11 August 2010 (UTC)
 * Phosphofructokinase and the related pages Phosphofructokinase 1, Phosphofructokinase 2
 * Viral neuraminidase, neuraminidase, Hemagglutinin, Hemagglutinin (influenza) and hemagglutinin-neuraminidase


 * I have done some work on phosphofructokinase and the related pages. Undoubtedly these pages need additional work, but hopefully they are now a little bit less confusing.  Cheers.  Boghog (talk) 22:28, 12 August 2010 (UTC)
 * Boghog, you are an utter legend ^_^

Ribosome mRNA image
I am the author of the ribosome image, and recently recieved a mesage saying that the image is inacurate since the mRNA appears to go through the large ribosomal subunit, which also appears to carry the A- and P-site tRNAs. and in reality the mRNA and A and P site are on the small ribosomal subunit. after cheking my sources it would seem in all of them that theA and P sites are in the large subunit, so i wanted to ask here wetheris this right, or i have to change the image.-LadyofHats (talk) 12:02, 10 September 2010 (UTC)

Make apolipoprotein L1 page easier to find please
Could someone make the Apolipoprotein L1 page easier to find?

It is located at http://en.wikipedia.org/wiki/APOL1

But APOA1 is located at http://en.wikipedia.org/wiki/Apolipoprotein_A1

And when I type in a search for apolipoprotein l, I don't find the APOL1 page.

I haven't worked on a Wikipedia page since the first year or so so don't have the skills.

But APOL1 has had some major news lately so needs to be very accessible.

Thanks, Jackie Aldridge, MLIS

(edited for misspelling, blush)

denature vs denaturate ?
Stumbled upon denature in Denaturation (biochemistry) - my feeling tells me it should be denaturate. Hm.. google thinks otherwise. What sounds more natural to you? Richiez (talk) 19:55, 22 September 2010 (UTC)


 * Google is right. Definitely denature.  Ka Faraq Gatri (talk) 22:15, 22 September 2010 (UTC)

Casein - improve section on Opioids
Hello everyone, I'm new to editing wiki pages and could use some help. I was poking around in an entry on Casein and stumble into a subsection titled "Opioid" under the Controversies section. I started a discussion entry about improving it and perhaps creating a new section "Bioactivity" to encompass the relevant information on the bioactive peptides and opioid receptor ligands derived from the Casein protein. Anyway, the section as it stands now seems woefully incomplete and heavily biased. I've listed some sources on the discussion page, but I could really use some help from some more qualified persons than myself to get the ball rolling on the changes.

Alister 77 (talk) 01:59, 30 September 2010 (UTC)

ChEMBL addition to the compound pages
Hi Everyone, I am the Chemical Content Curator for the ChEMBL group, based at the EBI in Hinxton, UK.

We are looking for some help to add direct links to our compound pages from the Wiki drug pages. Other sites such as ChemSpider are doing this and as we have direct links to ChemSpider and vice versa, it would be good to have these links from Wikipedia.

An example of this is:

Paracetamol

We would like to have a hyperlink in the same box as the ChemSpider one on the right hand side to link to:

https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL112

by displaying the id of: CHEMBL112 as the hyperlink.

Is there an autobot that could do this for us or any way that I can do this manually?

Thanks,

Louisa Bellis — Preceding unsigned comment added by 193.62.194.249 (talk • contribs)


 * This seems more relevant to the pharmacology project so I'll drop them a note to ask their opinion on this. SmartSE (talk) 12:24, 4 January 2011 (UTC) (here's a link) SmartSE (talk) 12:32, 4 January 2011 (UTC)

Microbial Noah's ark has hit a rock
I know that this falls under wikiproject microbiology or wikiproject tree of life, but in wikiproject MCB there are more computer savvy users. Basically, in wikipedia only medical bacteria and a few extra are present. I had in mind to rectify this. I have no idea how one does an automated mass creation of pages and I was warned against it (as there are 2,500 official prokaryotic species, so they might get deleted due to poor quality) so I was told to make a list so users can manually do it. So basically, I am using the database LPSN to create the taxonomy boxes and other info. I wrote a perl script and made this genera A to C, which I was hoping which I was hoping that someone could copy and paste a section under a redlink, press it and create a new page with some tweaks, such as adding links to List of bacterial genera named after personal names, List of bacterial genera named after mythological figures, List of bacterial genera named after geographical names, List of bacterial genera named after institutions etc.. to do so I used the nowiki tag for the content, but the newlines just get ignored and messes up lists. It would appear a simple task, but I do not know how to solve it. --Squidonius (talk) 05:03, 15 May 2011 (UTC)
 * If it is not solvable problem, it does not matter. However, volunteers of any skill are very much needed to make the articles. :) --Squidonius (talk) 12:42, 16 May 2011 (UTC)

Need help with a merge
The article IL-12 and IL-12 Receptor β1 Mutations seems somewhat redundant to the main article Interleukin 12 and I think that information at IL-12 and IL-12 Receptor β1 Mutations would be better served as a section of the main Interleukin 12. I know absolutely nothing about this subject however, and need someone with some more expertise to complete the merger. More information is at the Talk:Interleukin 12 page. Thanks in advance! -- Jayron  32  00:59, 5 July 2011 (UTC)

Claim of inaccurate molecular graphic at Urobilinogen
Hello all,

I was surfing about the encyclopaedia and landed on the urobilinogen article. I noticed that about a week ago, an IP address made the claim within the article that the graphic of the molecule is incorrect. I reverted that change and advised the editor to bring the concern to the article's talk page. However, that page doesn't seem to get much traffic, so I thought I'd mention it here too. As what I don't know about molecular biology could fill a warehouse, I thought that perhaps someone more knowledgeable in the subject can see what the problem is, if any, until the IP responds (assuming he or she does). Cheers, Northumbrian (talk) 04:35, 5 July 2011 (UTC)

Article: Nucleotides - Heading: Purine ribonucleotides - Reaction 1
In the text it says "This reaction is also shared with the pathways for the synthesis of the pyrimidine nucleotides, Trp, and His. " Which links to Tryptophan and Histadine, but they are amino acids, not nucleotides. Perhaps this should be ". . . synthesis of the pyrimidine nucleotides, Thymine and Cytosine"

Also, the next sentence "As a result of being on (a) such (a) major metabolic crossroad and the use of energy, this reaction is highly regulated." doesn't make sense.

Unfortunately I don't know enough biochemistry to make the correction, is someone more knowledgeable able to assist? 220.233.16.16 (talk) 08:59, 8 July 2011 (UTC)


 * . Thanks for the note. In the first sentence, Trp and His are in addition to the pyrimidine nucleotides, not types of pyrimidine nucleotides.  I've re-worded to resolve the ambiguity and to fix the following sentence.  The section now reads, "This reaction is also shared with the pathways for the synthesis of Trp, His, and the pyrimidine nucleotides. Being on a major metabolic crossroad and requiring much energy, this reaction is highly regulated."  The original text was added in November 2005 in this edit.  Adrian J. Hunter(talk•contribs) 14:17, 8 July 2011 (UTC)

Polysaccharide synthesis
I would like to write that polysaccharides are normally generated by addition of one monomer at a time (a monomer for the polymer is a monosaccharide or a disaccharide). This is true for the most abundant polysaccharides. But I haven't been able to find a reliable source that says this. Is it true? Can anyone help me with a reference? --Ettrig (talk) 12:17, 5 November 2011 (UTC)

Sex-determination system
Hello! I've been working on making the article sex determination system better, as a school project. Since I'm sure you all are much more knowledgeable than me, I was wondering if there's anything main headings I should add? I'm still steadily working on it, but I'm not entirely sure at what point I'm stepping on other articles' toes. It's such a broad topic; you could write pages upon pages and not be done! So, I just wanted to run this by you all here, and see what you thought. If you could just recommend any other main topics I should get to work on, that would be great. Thank you! Phorofor (talk) 23:48, 7 December 2011 (UTC)

Grocott/Gomori Methenamine-Silver Stains
I would like to make a small request for one histological issue. Is there (as once Alecisgreat wrote) any difference between Grocott's and Gomori's techniques of silver staining? There is only an article about the former, in which names and purposes are totally intermixed. Redirects and list in Silver stain entry also needs check-up. Lb.at.wiki (talk) 16:44, 14 June 2012 (UTC)

Help with Talk:Epstein-Barr virus naming controversy
I have been trying to normalize the naming of Epstein–Barr virus related pages on Wikipedia: Talk:Epstein–Barr virus. Any input would be greatly appreciated. Thank you! Walternmoss (talk) 23:14, 18 November 2013 (UTC)

Please advise on peptides in cosmetics
Please join our discussion at Talk:Peptide, or better, discuss the draft article at Draft:Peptides in skin care. (I have started a talk page at Draft talk:Peptides in skin care for that purpose.) --Hroðulf (or Hrothulf) (Talk) 14:29, 28 January 2014 (UTC)

New article for assessment
I believe Neuronal lineage marker falls under the scope of your project, and needs assessment. Haven't read it thoroughly, but it looks decently extensive. 0x0077BE [talk/contrib] 23:28, 28 February 2014 (UTC)

Terms do not redirect
While looking for some tight-junction related proteins, I found it hard to find some, though the articles do state the name I was looking for. For example: The Junctional Adhesion Molecule A can be found as F11 receptor. The 'symbols' box shows JAMA as one of the identifiers and even the article itself starts with "Junctional Adhesion Molecule A is...".

How do I make a search for 'JAM A' or 'Junctional Adhesion Molecule A' to actually redirect to the F11 receptor page?

Organizing G6PC articles
I'm looking at the article G6PC and it seems redundant with glucose 6-phosphatase. However G6PC seems to deal with the major isoform, and not G6PC2 or G6PC3. I'm unsure how to proceed, but am inclined to merge G6PC with glucose 6-phosphatase, and then add a mention of two other isoforms, with links to the appropriate articles. Is that appropriate? Or are G6PC and glucose 6-phosphatase separate concepts that deserve their own articles? I did put in a merge proposal: Talk:Glucose_6-phosphatase  --Gccwang (talk) 04:07, 15 August 2014 (UTC)

Rename proposed for cluster of differentiation articles
Please comment on the rename proposed at Talk:List_of_human_clusters_of_differentiation. There are many articles with titles in the form CDXXX which should be more descriptive to aid in categorization and search. Your input on the rename options proposed (or to propose alternatives) is requested. -Kyle(talk) 00:10, 24 August 2014 (UTC)

Stem cell and developmental biology Database
I would like to add an entry about a database in the fields of embryonic development, stem cell biology, regenerative medicine, disease mechanisms and therapeutic discovery. The database was established several years ago, is free, and is already in use by stem cell researchers and developmental biologists in academic and medical nonprofit institutions worldwide. It includes manually-curated molecular, cellular and anatomical data about tissues and cells, in addition to disease-related information and current therapeutic products available on the market or in development, aimed at application to stem cells and primary cells for treating degenerative diseases. It also contains in vivo and in vitro gene expression data, and guides translation from in vitro data to the clinical utility.

I would like to add the entry to the “Biological databases” section in the “Molecular and Cellular Biology category”. I would appreciate any input or suggestions as to how to go about adding the entry. Thanks in advance! Biology0345 (talk) 11:55, 23 September 2014 (UTC)

Retrotransposon Marker Article seems to be copied from journal article, since 2007
I am not sure whether this is the right place for my comment, but I think that the article Retrotransposon marker does not comply to wikipedia's standards. Since 2007 it is marked as containing copied content from journal articles and nothing has been done about it yet. I assume that one of the authors of these articles wrote the wikipedia article themselve, as it is such a specific topic. Maybe it should be removed or edited? 128.176.32.44 (talk) 09:31, 28 November 2014 (UTC)