Wilcox Octagon House

The Wilcox Octagon House is a historic home in Camillus, New York, USA, that was built in 1856 and was listed on the National Register of Historic Places in 1983. It was the farmhouse home of Isaiah Wilcox, who had a 40 acre farm. It is an octagon house of the type advocated by Orson Fowler, who wrote an influential book promoting use of octagonal home designs.

The Orchard Village neighborhood now occupies the majority of the old farm's land; the house remains on a plot of less than 1 acre.

It is located at 5420 West Genesee Street in Camillus.