William Burke

William Burke may refer to:


 * William Burke (pirate) (died 1699), Irish pirate active in the Caribbean, associate of William Kidd
 * William Burke (Burke and Hare murders) (1792–1829), Irish-Scots serial killer
 * William Burke (author) (1729–1798), English pamphleteer
 * William J. Burke (1862–1925), American politician and businessman
 * William Burke (baseball) (1865–1939), 19th-century baseball player
 * W. Lewis Burke (born 1948; born William Lewis Burke) American educator, historian
 * William L. Burke (1941–1996), astronomy, astrophysics, and physics professor at UC Santa Cruz
 * William Burke Miller (1904–1983), newspaper and radio reporter
 * William Burke (prior) (c. 1611–c. 1685), Irish Dominican
 * William Malachy Burke (1819–1879), Irish physician and Registrar General
 * William H. Burke, head coach of the College of William & Mary's football team in 1899
 * William H. Burke Jr. (1906–1975), American political figure
 * William mac Ulick Burke, 4th Clanricarde or Mac William Uachtar (d. 1430), Irish chieftain and noble
 * William Burke, 7th Earl of Clanricarde (died 1687), Irish peer
 * William Burke, Lord of Bealatury (fl. 1580s-1616), Irish noble and soldier
 * Willie Burke (born 1972), former Irish footballer
 * William Burke-White, American law professor and policy advisor