William Cayley

William Cayley may refer to:


 * Sir William Cayley, 1st Baronet (1610–1681) of the Cayley baronets
 * Sir William Cayley, 2nd Baronet (1635–c. 1708) of the Cayley baronets
 * William Cayley (MP) (died 1768), MP for Dover
 * William Cayley (Royal Navy officer) (1742–1801)
 * William Cayley (Canadian politician) (1807–1890), Canadian politician and lawyer