William Duane

William Duane may refer to:
 * William J. Duane (1780–1865), Irish-born American politician and lawyer from Pennsylvania
 * William J. Duane (Jesuit) (1868–?), Jesuit priest and president of Fordham University
 * William Duane (physicist) (1872–1935), American physicist
 * William Duane (journalist) (1760–1835), Irish-American journalist and newspaper publisher