William Grayson (disambiguation)


 * William Grayson (1740–1790) was a U.S. Senator from Virginia.

William Grayson may also refer to:


 * William Grayson Carter (died 1849), American politician from Kentucky and grandson of the senator
 * William J. Grayson (1788–1863), U.S. Representative from South Carolina
 * William W. Grayson (1876-1941), American soldier, known for firing the shot that started the Philippine–American War
 * SS William Grayson, a Liberty ship, named for the senator