William Guise (disambiguation)

William Guise was an orientalist.

William Guise may also refer to:


 * Sir William Guise, 5th Baronet (1737–1783), MP for Gloucestershire
 * Sir William Vernon Guise, 4th Baronet (1816–1887), of the Guise baronets
 * Sir William Francis George Guise, 5th Baronet (1851–1920), of the Guise baronets