William Henry and Lilla Luce Harrison House

William Henry and Lilla Luce Harrison House, also known as the Dr. Samuel Harris House, is a historic home located at Cape Girardeau, Missouri. It was built in 1897, and is a $2 1/2$-story, free classic Queen Anne style brick dwelling. It has a steeply pitched side-gable roof with projecting dormers. It features a wraparound porch with circular verandah added between 1900 and 1908.

It was listed on the National Register of Historic Places in 2005. It is located in the Courthouse-Seminary Neighborhood Historic District.