William Humphrey

William Humphrey may refer to:


 * William Humphrey (engraver) (1740–1810), English printseller
 * William Humphrey (cricketer) (1843–1918), English cricketer
 * William Humphrey (writer) (1924–1997), American novelist
 * William Humphrey (Northern Ireland politician) (born 1967), Northern Irish unionist
 * William E. Humphrey (1862–1934), American politician
 * William F. Humphrey (1860–1928), Canadian politician in the Legislative Assembly of New Brunswick
 * William J. Humphrey (1875–1942), film director
 * Willie Humphrey (1900–1994), jazz clarinetist
 * William Humfrey (died 1579), mining promoter, Assay Master at the Royal Mint