William Humphreys

William Humphreys may refer to:
 * William Y. Humphreys (1890–1933), U.S. Congressman from Mississippi
 * William Jackson Humphreys (1862–1949), American physicist and meteorologist
 * William Humphreys Jackson (1839–1915), U.S. Congressman from Maryland
 * William Humfrey (died 1579), also written William Humphreys, Elizabethan goldsmith
 * William Benbow Humphreys (1889–1965), South African politician
 * William Humphreys (footballer), English footballer
 * Billy Humphreys (1884–?), English footballer