William Jacobs

William Jacobs may refer to:
 * W. W. Jacobs (1863–1943), short story writer
 * William H. Jacobs (1831–1882), Wisconsin legislator and banker
 * Will Jacobs (born 1955), American comics writer
 * William Elmer Jacobs, baseball player
 * William Jacobs (producer) (1887–1953), film producer
 * William R. Jacobs Jr. (born 1955), professor of microbiology, immunology and genetics