William Lyon

William Lyon may refer to:
 * William Lyon (film editor) (1903–1974), American film editor
 * William John Lyon (1898–1941), New Zealand politician
 * William Lyon (bishop) (died 1617), English bishop
 * William Lyon (priest) (1883–1961), Anglican Archdeacon of Loughborough
 * William Durie Lyon (died 1893), Ontario businessman and politician
 * William C. Lyon (born 1841), American politician
 * William P. Lyon (1822–1913), Wisconsin jurist and soldier
 * William Radenhurst Richmond Lyon (1820–1854), first reeve of Richmond, Ontario
 * Bill Lyon (1886–?), Australian rules footballer
 * Billy Lyon (born 1973), American football player
 * William Lyon (general) (1923–2020), USAF general