William Rutherford

William Rutherford may refer to:
 * Bill Rutherford, British professor of biochemistry
 * Bill Rutherford (footballer), Scottish footballer
 * Bill Rutherford (politician), Oregon politician
 * William Gunion Rutherford (1853–1907), Scottish scholar
 * William Rutherford (mathematician) (1798–1871), English mathematician
 * William Rutherford (physiologist) (1839–1899), British physiologist
 * Sir William Rutherford, 1st Baronet (1853–1927), British politician, MP for West Derby and Edge Hill
 * Willie Rutherford (1945–2010), Australian football player