William Vaughan

William Vaughan may refer to:


 * William Vaughan (philanthropist) (died 1580), English landowner, farmer and philanthropist
 * Sir William Vaughan (writer) (1575–1641), Welsh writer and colonial investor
 * Sir William Vaughan (Royalist) (died 1649), English royalist commander in the First English Civil War
 * William Gwyn Vaughan (1680s–1753), Welsh politician
 * William Vaughan (MP) (c. 1707–1775), Member of Parliament for and Lord Lieutenant of Merioneth
 * William Vaughan (merchant) (1752–1850), English West India merchant and author
 * William Vaughan (bishop) (1814–1902), Roman Catholic Bishop of Plymouth
 * William Wirt Vaughan (1831–1878), member of the United States House of Representatives
 * William Wyamar Vaughan (1865–1938), British educationalist
 * William Vaughan (footballer) (1898 – 1976), English footballer
 * William E. Vaughan (1915–1977), American columnist and author
 * William Vaughan (art historian) (fl. 1972–2015), British art historian
 * William Edward Vaughan (fl. 1984–2013), Irish historian
 * W. Harry Vaughan (1900–?), founder of the Georgia Tech Research Institute