William Worthington

William Worthington may refer to:


 * William Worthington (actor) (1872–1941), American silent film actor and director
 * William Worthington (priest) (1703–1778), Anglican priest and theological writer
 * William Barton Worthington (1854–1939), British civil engineer
 * William Grafton Delaney Worthington (1785–1856), American lawyer, judge, and politician
 * William H. Worthington (1828–1862), American farmer, lawyer, and military officer
 * William Jackson Worthington (1833–1914), American politician
 * William Chesley Worthington (1903–2002), editor of The Providence Journal and editor of the Brown Alumni Monthly