William Wylie

William Wylie may refer to:
 * William Campbell Wylie (1905–1992), New Zealand-born Chief Justice of Borneo
 * W. Derek Wylie (1918–1998), British physician, dean of the Royal College of Anaesthetists
 * William Duncan Wylie (1900–1981), Canadian politician, farmer, public servant and federal
 * William Howie Wylie (1833–1891), Scottish journalist and Baptist minister
 * William M. Wylie (1928–2006), U.S. politician, farmer, and businessman from Nebraska