Wyo

Wyo or WYO may refer to:


 * Wyoming, a state in USA
 * Wyo, California, a community in Glenn County, California
 * Wessex Youth Orchestra, an orchestra in Poole, England
 * Williamsburg Youth Orchestra, an orchestra in Williamsburg, Virginia
 * World Youth Organization, a non-profit organization in Chennai, India
 * WYO, a candidate phylum of bacteria
 * José Miguel Monzón aka El Gran Wyoming, a Spanish humorist