XPF

XPF may refer to:
 * CFP franc, the currency used in the French overseas collectivities (collectivités d’outre-mer, or COM) of French Polynesia, New Caledonia and Wallis and Futuna
 * ERCC4, an enzyme that in humans is encoded by the ERCC4 gene
 * The Extended Control Program Facility (XPF), a component of the IBM i operating system
 * X Prize Foundation; offers inducement prize contests to encourage spaceflight and other technological development
 * a LMMS Preset File