Yun Chae-ok

Yun Chae-ok (born 9 May 1963) is a Korean-born scientist and professor of Bioengineering at Hanyang University, Seoul, Korea.

Biography and education
Yun received her Bachelor of Science in biology in 1986 and in 1988 her Master of Science in biology, both in Sogang University, located in Seoul. She finished her Ph.D. in Cell and Molecular Biology in 1996 at the Illinois Institute of Technology. She continued her postdoctoral education at Harvard Medical School, for 2 years, and moved back to Korea in 2000.

Research
Her research interests approach cancer gene therapy, immunotherapy, angiogenesis, the combination of viral with non-viral vectors, nanomedicine, and tumor biology.

Selected publications

 * Fukumura D, Gohongi T, Kadambi A, Izumi Y, Ang J, Yun CO, Buerk DG, Huang PL, Jain RK. The predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proceedings of the National Academy of Sciences. 2001 Feb 27;98(5):2604-9.
 * Kim JH, Lee YS, Kim H, Huang JH, Yoon AR, Yun CO. Relaxin expression from tumor-targeting adenoviruses and its intratumoral spread, apoptosis induction, and efficacy. Journal of the National Cancer Institute. 2006 Oct 18;98(20):1482-93.
 * Yoo JY, Kim JH, Kwon YG, Kim EC, Kim NK, Choi HJ, Yun CO. VEGF-specific short hairpin RNA–expressing oncolytic adenovirus elicits potent inhibition of angiogenesis and tumor growth. Molecular Therapy. 2007 Feb 1;15(2):295-302.
 * Lee YS, Kim JH, Choi KJ, Choi IK, Kim H, Cho S, Cho BC, Yun CO. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model. Clinical cancer research. 2006 Oct 1;12(19):5859-68.
 * Son YG, Kim EH, Kim JY, Kim SU, Kwon TK, Yoon AR, Yun CO, Choi KS. Silibinin sensitizes human glioma cells to TRAIL-mediated apoptosis via DR5 up-regulation and down-regulation of c-FLIP and survivin. Cancer research. 2007 Sep 1;67(17):8274-84.

Honors and awards
She was elected to the National Academy of Engineering of Korea.