Amir Manbachi

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Amir Manbachi
NationalityIranian-Canadian
Alma materUniversity of Toronto
OccupationAcademic
Notable workTowards Ultrasound-guided Spinal Fusion Surgery (2018)

Amir Manbachi is an Iranian-Canadian academic and researcher.[1][2] He is the co-founder and current director of HEPIUS Innovation Lab at Johns Hopkins University.[3]

Biography[edit]

Manbachi is of Iranian descent.[3][2] He attended the University of Toronto, where he completed his bachelor's degree in applied sciences (BASc) in the Engineering Science (Physics) program.[4] Later, he obtained his master's degree and a PhD in biomedical engineering at the University of Toronto.[4][3][5] During his third year as a PhD candidate, he, along with his university advisers, established Spinesonics Medical which developed a sensor designed to aid in vertebral screw insertion procedures.[6][7] They received a $50,000 provincial grant to support their research and development efforts.[6]

In 2016, Manbachi joined the Department of Biomedical Engineering at Johns Hopkins University as a research faculty member.[4][8] At Johns Hopkins University, he co-founded HEPIUS Innovation Labs and now serves as its director.[9][10] He also served as an associate director of the Center for Bioengineering Innovation and Design.[11]

In 2018, Manbachi and Nao J. Gamo began researching ultrasound technology with the potential to target and "burn" brain tumors.[11] They received a total of $250,000 in grant funding from Hopkins, Maryland Technology Development Corp., and the Wallace H. Coulter Foundation for this purpose.[11]

In 2020, Manbachi and a team co-led by Nicholas Theodore at Johns Hopkins Medicine were awarded a $13.5M grant from the Defense Advanced Research Projects Agency (DARPA) to research wearable and implantable ultrasound technologies for spinal cord injury patients.[12][13]

In 2022, Manbachi received Baltimore Business Journal's 40 under 40 award, and secured a Johns Hopkins Discovery award.[3]

In 2023, the HEPIUS Innovation Lab at Hopkins, led by Manbachi, received a Food and Drug Administration Breakthrough Device Designation for a novel ultrasound imaging implant.[10][14]

Awards and recognition[edit]

  • 40 under 40 by Baltimore Business Journal[3]
  • University of Toronto's 2015 Inventor of the year award
  • Robert B. Pond Sr. Excellence in Teaching Excellence Award, Johns Hopkins University, Whiting School of Engineering[15]
  • Johns Hopkins Inst for Clinical and Translational Research’s KL2 Clinical Research Scholar, 2020
  • FDA Breakthrough designation pathway awarded to his MUSIC device invention, 2023

Selected publications[edit]

  • Manbachi, Amir; Cobbold, Richard S C (November 2, 2011). "Development and Application of Piezoelectric Materials for Ultrasound Generation and Detection". Ultrasound. 19 (4): 187–196. doi:10.1258/ult.2011.011027. S2CID 56655834 – via CrossRef.
  • Abramson, Haley G.; Curry, Eli J.; Mess, Griffin; Thombre, Rasika; Kempski-Leadingham, Kelley M.; Mistry, Shivang; Somanathan, Subhiksha; Roy, Laura; Abu-Bonsrah, Nancy; Coles, George; Doloff, Joshua C.; Brem, Henry; Theodore, Nicholas; Huang, Judy; Manbachi, Amir (February 2, 2022). "Automatic detection of foreign body objects in neurosurgery using a deep learning approach on intraoperative ultrasound images: From animal models to first in-human testing". Frontiers in Surgery. 9: 1040066. doi:10.3389/fsurg.2022.1040066. PMC 9748097. PMID 36532130.
  • Aghabaglou, Fariba; Ainechi, Ana; Abramson, Haley; Curry, Eli; Kaovasia, Tarana Parvez; Kamal, Serene; Acord, Molly; Mahapatra, Smruti; Pustavoitau, Aliaksei; Smith, Beth; Azadi, Javad; Son, Jennifer K.; Suk, Ian; Theodore, Nicholas; Tyler, Betty M.; Manbachi, Amir (October 2, 2022). "Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic". Microcirculation (New York, N.Y.: 1994). 29 (6–7): e12770. doi:10.1111/micc.12770. PMC 9786257. PMID 35611457.
  • Kempksi Leadingham, K.M.; Abramson, H.G.; Perdomo-Pantoja, A.; Thombre, R.; Liu, J.; Norman, M.; Chavez, F.; Morrison, K.; Suk, I.; Gordon, C.; Armand, M.; Manbachi, A. (2022). "Design of a Custom Flexible Ultrasound Transducer as an Implantable Cranial Sensor for Long-Term Post-Operative Monitoring of Brain Tumor Regrowth". 2022 IEEE International Ultrasonics Symposium (IUS). pp. 1–4. doi:10.1109/IUS54386.2022.9958345. ISBN 978-1-6654-6657-8. S2CID 254155937.
  • Routkevitch, Denis; Hersh, Andrew M.; Kempski, Kelley M.; Kerensky, Max; Theodore, Nicholas; Thakor, Nitish V.; Manbachi, Amir (October 2, 2022). "FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation". 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS). Vol. 2022. pp. 610–614. doi:10.1109/biocas54905.2022.9948639. ISBN 978-1-6654-6917-3. PMC 9870043. PMID 36695674.

Bibliography[edit]

  • Manbachi, Amir; M. Kempski Leadingham, Kelley; J. Curry, Eli (28 November 2022). The Abundant Promise of Ultrasound in Neurosurgery: A Broad Overview and Thoughts on Ethical Paths to Realizing Its Benefits. ISBN 9781510657250.
  • Manbachi, Amir (27 May 2018). Towards Ultrasound-guided Spinal Fusion Surgery. Springer International Publishing. ISBN 9783319806648.

References[edit]

  1. ^ Staff, Daily Record (March 12, 2021). "Hopkins professors earn grants through Bisciotti Foundation Translational Fund".
  2. ^ a b "استاد ایرانی دانشگاه جانز هاپکینز: جامعه علمی باید از حق دفاع کند". صدای آمریکا. December 25, 2022.
  3. ^ a b c d e "40 Under 40: Amir Manbachi, Johns Hopkins University".
  4. ^ a b c "The path to a faculty position: Q & A with alumnus Amir Manbachi". Biomedical Engineering - University of Toronto. June 23, 2016.
  5. ^ "Princely Persian performers". The Varsity. January 23, 2007.
  6. ^ a b "Job situation may get worse for Ontario graduates". The Canadian Press. September 11, 2013.
  7. ^ Babbage, Maria (September 11, 2013). "Challenges just beginning for Ontario, Canada's most populous have-not province". CTVNews.
  8. ^ "Trump fires acting AG over her stance not to enforce travel ban". Baltimore Sun. January 31, 2017.
  9. ^ "Amir Manbachi".
  10. ^ a b "Johns Hopkins lab aiming to improve spinal cord injury care hits FDA milestone".
  11. ^ a b c "Hopkins-born venture aims to use ultrasound technology to treat brain tumors".
  12. ^ "Focused Ultrasound for Spinal Cord Injury: Johns Hopkins Receives Funding for New Device". October 30, 2020.
  13. ^ "$13.48M Awarded to Johns Hopkins Scientists to Develop Implantable Ultrasound Devices for Patients with Spinal Cord Injury - Johns Hopkins Technology Ventures". ventures.jhu.edu. October 30, 2020.
  14. ^ "Fire Awards 2023: HEPIUS Innovation Lab".
  15. ^ "Amir Manbachi, Ph.D., M.Sc., Assistant Professor of Neurosurgery". Johns Hopkins Medicine.
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