HgcG RNA

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HgcG RNA
Identifiers
SymbolHgcG
RfamRF00064
Other data
RNA typeGene
Domain(s)Archaea
SOSO:0000655
PDB structuresPDBe

The HgcG RNA gene is a non-coding RNA that was identified computationally and experimentally verified in AT-rich hyperthermophiles.[1] The genes from this screen were named hgcA through hgcG ("high GC"). HgcG is of unknown function. hgcG is significantly similar to a region of the Archaeoglobus fulgidus genome. The genes were named hgcA through hgcG ("high GC"). It was later identified as Pab40 H/ACA snoRNA with rRNA targets.[2]

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References[edit]

  1. ^ Klein RJ, Misulovin Z, Eddy SR (May 2002). "Noncoding RNA genes identified in AT-rich hyperthermophiles". Proceedings of the National Academy of Sciences of the United States of America. 99 (11): 7542–7547. Bibcode:2002PNAS...99.7542K. doi:10.1073/pnas.112063799. PMC 124278. PMID 12032319.
  2. ^ Muller S, Leclerc F, Behm-Ansmant I, Fourmann JB, Charpentier B, Branlant C (May 2008). "Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs". Nucleic Acids Research. 36 (8): 2459–2475. doi:10.1093/nar/gkn077. PMC 2377435. PMID 18304947.

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