Mir-484 microRNA precursor family

From Wikipedia, the free encyclopedia
mir-484
Identifiers
Symbolmir-484
RfamRF00783
miRBase familyMIPF0000219
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-484 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms. The precursor hairpin of miR-484 is transcribed directly and contains a 7-methylguanylated cap. The biogenesis of miR-484 is independent of Drosha.

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Further reading[edit]

  • Wang K, Long B, Jiao JQ, Wang JX, Liu JP, Li Q, Li PF (April 2012). "miR-484 regulates mitochondrial network through targeting Fis1". Nature Communications. 3: 781. Bibcode:2012NatCo...3..781W. doi:10.1038/ncomms1770. PMID 22510686.
  • Hu Z, Dong J, Wang LE, Ma H, Liu J, Zhao Y, Tang J, Chen X, Dai J, Wei Q, Zhang C, Shen H (April 2012). "Serum microRNA profiling and breast cancer risk: the use of miR-484/191 as endogenous controls". Carcinogenesis. 33 (4): 828–34. doi:10.1093/carcin/bgs030. PMID 22298638.
  • Li QL, Ju ZH, Huang JM, Li JB, Li RL, Hou MH, Wang CF, Zhong JF (April 2011). "Two novel SNPs in HSF1 gene are associated with thermal tolerance traits in Chinese Holstein cattle". DNA and Cell Biology. 30 (4): 247–54. doi:10.1089/dna.2010.1133. PMID 21189066.
  • Bimpaki EI, Iliopoulos D, Moraitis A, Stratakis CA (June 2010). "MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis". Clinical Endocrinology. 72 (6): 744–51. doi:10.1111/j.1365-2265.2009.03725.x. PMC 3003432. PMID 19849700.
  • Tang X, Muniappan L, Tang G, Ozcan S (February 2009). "Identification of glucose-regulated miRNAs from pancreatic {beta} cells reveals a role for miR-30d in insulin transcription". RNA. 15 (2): 287–93. doi:10.1261/rna.1211209. PMC 2648717. PMID 19096044.
  • Xie M, Li M, Vilborg A, Lee N, Shu MD, Yartseva V, Šestan N, Steitz JA (December 2013). "Mammalian 5'-capped microRNA precursors that generate a single microRNA". Cell. 155 (7): 1568–80. doi:10.1016/j.cell.2013.11.027. PMC 3899828. PMID 24360278.

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