Mona Mostafa Mohamed

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Mona Mostafa Mohamed
Academic work
InstitutionsCairo University

Mona Mostafa Mohamed is an Egyptian doctor and head of the Cancer Biology Research Laboratory at Cairo University in Giza, Egypt. In 2005 she was granted the Avon Foundation-AACR International Scholar Award for her dedication to breast cancer research. Mohamed is known for her research on locally activated breast cancer, metastatic breast cancer, and inflammatory breast cancer.

Education and career[edit]

Mohamed has a B.S. (1991) and a Ph.D. (2002) from Cairo University.[1] She was a postdoctoral researcher at Wayne State School of Medicine from 2005 until 2007.[2][better source needed] In 2007, she was awarded a start up fund from the Avon Foundation to create the first research lab in Egypt specific to studying breast cancer biology which is located at Cairo University.[3] As of 2022 she is an associate professor at Cairo University.[4]

Mohamed is known for her work in breast cancer, particularly on the role of multi functional enzymes.[5] Her research has examined the conditions for women with inflammatory breast cancer in Egypt,[6] and white blood cells from patients with inflammatory breast cancer.[7][8]

Selected publications[edit]

  • Mohamed, Mona Mostafa; Sloane, Bonnie F. (2006). "Cysteine cathepsins: multifunctional enzymes in cancer". Nature Reviews Cancer. 6 (10): 764–775. doi:10.1038/nrc1949. ISSN 1474-175X. PMID 16990854. S2CID 26463930.
  • Mohamed, Mona M.; El-Ghonaimy, Eslam A.; Nouh, Mohamed A.; Schneider, Robert J.; Sloane, Bonnie F.; El-Shinawi, Mohamed (2014-01-01). "Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties". The International Journal of Biochemistry & Cell Biology. 46: 138–147. doi:10.1016/j.biocel.2013.11.015. ISSN 1357-2725. PMC 3928544. PMID 24291763.
  • Ibrahim, Sherif Abdelaziz; Gadalla, Ramy; El-Ghonaimy, Eslam A.; Samir, Omnia; Mohamed, Hossam Taha; Hassan, Hebatallah; Greve, Burkhard; El-Shinawi, Mohamed; Mohamed, Mona Mostafa; Götte, Martin (2017). "Syndecan-1 is a novel molecular marker for triple negative inflammatory breast cancer and modulates the cancer stem cell phenotype via the IL-6/STAT3, Notch and EGFR signaling pathways". Molecular Cancer. 16 (1): 57. doi:10.1186/s12943-017-0621-z. ISSN 1476-4598. PMC 5341174. PMID 28270211.
  • Nouh, Mohamed A; Mohamed, Mona M; El-Shinawi, Mohamed; Shaalan, Mohamed A; Cavallo-Medved, Dora; Khaled, Hussein M; Sloane, Bonnie F (2011). "Cathepsin B: a potential prognostic marker for inflammatory breast cancer". Journal of Translational Medicine. 9 (1): 1. doi:10.1186/1479-5876-9-1. ISSN 1479-5876. PMC 3022726. PMID 21199580.

Awards and honors[edit]

In 2005, Mohamed won the Avon Foundation International Scholar Award in Breast Cancer Research.[9][10] In 2012, she was admitted into the United States' State Departments' Women in Science Hall of Fame for the Middle East and North Africa.[9][11][better source needed] In 2014 she was awarded the Arab Women Organization Prize in Science and Technology.[12][better source needed]

References[edit]

  1. ^ "Dr. Mona Mostafa Mohamed's biography". Cairo University Scholars.
  2. ^ "Mentorship with Dr. Sloane leads to new breast cancer research lab in Egypt". School of Medicine News. May 5, 2009. Retrieved 2022-10-29.
  3. ^ Karim, Ahmed A.; Khalil, Radwa; Moustafa, Ahmed (2021-07-27). Female Pioneers from Ancient Egypt and the Middle East: On the Influence of History on Gender Psychology. Springer Nature. p. 55. ISBN 978-981-16-1413-2.
  4. ^ "Mona Mostafa Mohamed". Cairo University. Retrieved 2022-12-17.
  5. ^ Mohamed, Mona Mostafa; Sloane, Bonnie F. (2006). "multifunctional enzymes in cancer". Nature Reviews Cancer. 6 (10): 764–775. doi:10.1038/nrc1949. ISSN 1474-175X. PMID 16990854. S2CID 26463930.
  6. ^ Mohamed, MM; El-Shinawi, M; Cavallo-Medved, D; Sobhy, M; Nouh, MA; Abdelwahab, SF; Sloane, BF (2009). "Monocytes/macrophages and natural killer cells characterize the tumor microenvironment of inflammatory breast cancer in Egyptian patients". Cancer Research. 69 (2_Supplement): 1054. doi:10.1158/0008-5472.sabcs-1054. ISSN 0008-5472.
  7. ^ Mohamed, Mona M.; El-Ghonaimy, Eslam A.; Nouh, Mohamed A.; Schneider, Robert J.; Sloane, Bonnie F.; El-Shinawi, Mohamed (2014-01-01). "Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties". The International Journal of Biochemistry & Cell Biology. 46: 138–147. doi:10.1016/j.biocel.2013.11.015. ISSN 1357-2725. PMC 3928544. PMID 24291763.
  8. ^ Mohamed, Hossam Taha; El-Husseiny, Noura; El-Ghonaimy, Eslam A.; Ibrahim, Sherif Abdelaziz; Bazzi, Zainab A.; Cavallo-Medved, Dora; Boffa, Michael B.; El-Shinawi, Mohamed; Mohamed, Mona Mostafa (2018-03-01). "IL-10 correlates with the expression of carboxypeptidase B2 and lymphovascular invasion in inflammatory breast cancer: The potential role of tumor infiltrated macrophages". Current Problems in Cancer. SI: Cervical Cancer. 42 (2): 215–230. doi:10.1016/j.currproblcancer.2018.01.009. ISSN 0147-0272. PMID 29459177.
  9. ^ a b "Ambassador Patterson Honors Egyptian Women in Science". Targeted News Service; Washington, D.C. [Washington, D.C]. 23 April 2012 – via ProQuest.
  10. ^ Sciences (TWAS), The World Academy of; Alexandrina, Bibliotheca; Council, National Research; Studies, Division on Earth and Life; Sciences, Board on Life; Potential, Committee on Developing a Framework for an International Faculty Development Project on Education About Research in the Life Sciences with Dual Use (2013-07-28). Developing Capacities for Teaching Responsible Science in the MENA Region: Refashioning Scientific Dialogue. National Academies Press. ISBN 978-0-309-28639-8.
  11. ^ "CAIRO - Mona Mostafa Mohamed". U.S. Embassy in Jordan. Retrieved 2022-10-29.
  12. ^ "Mona Mostafa". Galala University. Retrieved 2022-03-14.

External links[edit]

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