Talk:Gene knock-in

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Genetics task force (assessed as Mid-importance).
	This article is supported by the Molecular and Cell Biology task force (assessed as Mid-importance).

Biology Mid‑importance

	Biology portal Gene knock-in is part of the WikiProject Biology, an effort to build a comprehensive and detailed guide to biology on Wikipedia. Leave messages on the WikiProject talk page.BiologyWikipedia:WikiProject BiologyTemplate:WikiProject BiologyBiology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Wiki Education Foundation-supported course assignment[edit]

This article was the subject of a Wiki Education Foundation-supported course assignment, between 24 March 2020 and 24 April 2020. Further details are available on the course page. Student editor(s): Loosepa.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 22:09, 16 January 2022 (UTC)[reply]

Technical Detail[edit]

Are both alleles affected or only one via knock-in technology? The article is unspecific pertaining to that question. 84.112.136.52 (talk) 19:50, 25 May 2014 (UTC)[reply]

Untitled[edit]

Hi, I think that may be confusing to say that "the difference between knock in and transgenic technology" or something like that. In fact, the knock-in gene targeting methods are a subset of transgenesis. In other words, if you knock-out or knock-in a gene you are doing transgenesis because the resultant organism (mouse, fly, etc) carries an exogenous piece of DNA. May be we can say "the difference between knock-in and OTHER transgenesis technologies". It also could be useful to remark that the main difference between knock-out and knock-in is that, even though both are targeted mutagenesis methods, knock-out results in gene disruption and loss of function, whereas knock-in results in gene replacement with the intention to investigate the behaviour of an in-vitro modified version of the wild type gene. I am sorry for my english, I am still learning your language.

External links modified[edit]

Hello fellow Wikipedians,

I have just modified one external link on Gene knockin. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

Added archive https://web.archive.org/web/20080125042104/http://www.ihcworld.com/neuroscience/genetic.htm to http://www.ihcworld.com/neuroscience/genetic.htm

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 18 January 2022).

If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 12:11, 12 October 2017 (UTC)[reply]