Talk:Vagotomy

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sorry, but is it really necessary to include that sentence about "not to be confused with vasectomy?" —Preceding unsigned comment added by 69.14.124.118 (talk) 00:00, 1 August 2010 (UTC)[reply]

B12 deficiency[edit]

The article reads: "One potential side effect of vagotomy is a vitamin B12 deficiency. As vagotomy decreases gastric secretion, intrinsic factor production can be impaired. Intrinsic factor is needed to absorb vitamin B12 efficiently from food..."

Is this correct? Does vagotomy result in less production of IF? I had assumed B12 deficiency occurred due to achlorhydria rendering pepsin inactive, so it cannot liberate B12 from its carrier/meat protein. As a result, haptocorrin is unable to bind. In that case oral B12 supplements would still be effective, as they are not protein bound, but still dependent on IF for ileal absorption.Coursesix (talk) 02:49, 9 April 2020 (UTC)[reply]