User:Mr. Ibrahem/Midodrine
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| Clinical data | |
|---|---|
| Trade names | Amatine, Proamatine, Gutron, others |
| Other names | Midodrine hydrochloride, 2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxy-ethyl]-acetamide |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a602023 |
| License data | |
| Pregnancy category |
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| Routes of administration | By mouth |
| Drug class | α1-selective adrenergic agonist[1] |
| Legal status | |
| Legal status | |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C12H18N2O4 |
| Molar mass | 254.286 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
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Midodrine is a medication used for low blood pressure with standing that results in significant symptoms.[1][3] Evidence of benefit; however, was pending as of 2015.[1] It is taken by mouth.[1]
Common side effects include numbness, itchiness, urinary retention, and high blood pressure.[1] Other side effects may include slow heart rate.[1] It should not be used in people with an aortic aneurysm, heart failure, or prior heart attack.[3] Use in pregnancy may harm the baby.[3] It is a α1-selective adrenergic agonist.[1]
Midodrine was approved for medical use in the United States in 1996.[1] It is available as a generic medication.[3] In the United Kingdom 100 tablets of 5 mg costs the NHS £75 as of 2021.[3] In the United States this amount costs about 44 USD.[4]
References[edit]
- ^ a b c d e f g h i j "Midodrine Monograph for Professionals". Drugs.com. Archived from the original on 20 January 2021. Retrieved 18 November 2021.
- ^ "Proamatine- midodrine hydrochloride tablet". DailyMed. Archived from the original on 15 August 2021. Retrieved 14 August 2021.
- ^ a b c d e f BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 202. ISBN 978-0857114105.
- ^ "Midodrine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 23 October 2016. Retrieved 18 November 2021.