User:Mr. Ibrahem/Phenazopyridine

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Mr. Ibrahem/Phenazopyridine
Clinical data
Trade namesPyridium, others
AHFS/Drugs.comMonograph
MedlinePlusa682231
License data
Pregnancy
category
  • B
Routes of
administration
By mouth
Drug classAzo dye[1]
Legal status
Legal status
  • CA: prescription only in BC and ON
  • US: OTC
Identifiers
  • 3-phenyldiazenylpyridine-2,6-diamine
Chemical and physical data
FormulaC11H11N5
Molar mass213.244 g·mol−1
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Phenazopyridine, sold under the brand name Pyridium among others, is a medication used to help with the discomfort caused by urinary tract infection, surgery, or injury to the urinary tract.[1] For urinary tract infection it may be used together with antibiotics for the first two days.[1] It is taken by mouth.[1]

Side effects may include orange colored urine and other body fluids.[1][2] Other side effects may include yellowish skin, methemoglobinemia, sulfhemoglobinemia, and hemolytic anemia.[1][3] Use is not recommended in those with kidney or liver problems.[1] There is no evidence of harm with use during pregnancy.[4] Use during breastfeeding is not recommended.[4] Phenazopyridine is a azo dye and how it works is not entirely clear.[1]

Phenazopyridine came into medical use in the 1930s.[5] It maybe available as a generic medication and over the counter.[1][6] In the United States six doses of 200 mg costs about 8 USD as of 2020.[7] It is not easily available in Canada as of 2015, though some pharmacies will make it.[8]

References[edit]

  1. ^ a b c d e f g h i j k "Phenazopyridine Hydrochloride Monograph for Professionals". Drugs.com. Archived from the original on 25 July 2019. Retrieved 13 October 2020.
  2. ^ a b Moldwin, Robert M. (2017). Urological and Gynaecological Chronic Pelvic Pain: Current Therapies. Springer. p. 237. ISBN 978-3-319-48464-8. Archived from the original on 2021-08-28. Retrieved 2020-10-13.
  3. ^ "Phenazopyridine". Drugs and Lactation Database (LactMed). National Library of Medicine (US). October 31, 2018. Archived from the original on 26 February 2021. Retrieved 13 October 2020.
  4. ^ a b "Phenazopyridine Use During Pregnancy". Drugs.com. Archived from the original on 2021-01-24. Retrieved 2020-10-13.
  5. ^ Sneader, Walter (2005). Drug Discovery: A History. John Wiley & Sons. p. 383. ISBN 978-0-471-89979-2. Archived from the original on 2021-08-28. Retrieved 2020-10-13.
  6. ^ Wang, A; Nizran, P; Malone, MA; Riley, T (September 2013). "Urinary tract infections". Primary care. 40 (3): 687–706. doi:10.1016/j.pop.2013.06.005. PMID 23958364.
  7. ^ "Phenazopyridine Prices and Phenazopyridine Coupons". GoodRx. Archived from the original on 17 June 2019. Retrieved 13 October 2020.
  8. ^ "Calgary doctor answers 'burning' questions about bladder infections". CBC. Archived from the original on 29 August 2018. Retrieved 13 October 2020.