User:Mr. Ibrahem/Phenoxybenzamine
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| Clinical data | |
|---|---|
| Trade names | Dibenzyline |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a682059 |
| Pregnancy category |
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| Routes of administration | By mouth |
| Drug class | Alpha blocker[1] |
| Pharmacokinetic data | |
| Elimination half-life | 24 hours |
| Identifiers | |
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| Chemical and physical data | |
| Formula | C18H22ClNO |
| Molar mass | 303.83 g·mol−1 |
| 3D model (JSmol) | |
| Chirality | Racemic mixture |
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| (verify) | |
Phenoxybenzamine, sold under the brand name Dibenzyline among others, is a medication used to manage pheochromocytoma, peripheral vascular disease, and urinary retention.[1] It is taken by mouth.[1] Effects begin in hours and can last for a week.[1]
Common side effects include a stuffy nose, small pupils, and low blood pressure with standing.[1] Other side effects may include heart problems as a result of a faster heart rate.[1] It should not be used in people with porphyrias.[2] It is an alpha blocker.[1]
Phenoxybenzamine was approved for medical use in the United States in 1953.[1] It is available as a generic medication.[3] In the United States 60 tablets of 10 mg costs about 1,800 USD as of 2021.[3] In the United Kingdom this amount costs the NHS about £240.[2]
References[edit]
- ^ a b c d e f g h i j "Phenoxybenzamine Monograph for Professionals". Drugs.com. Archived from the original on 13 August 2021. Retrieved 28 October 2021.
- ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 195. ISBN 978-0857114105.
- ^ a b "Phenoxybenzamine Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 31 October 2016. Retrieved 28 October 2021.