User:Mr. Ibrahem/Prucalopride
Clinical data | |
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Trade names | Prudac, Resolor, Resotran, other |
AHFS/Drugs.com | Monograph |
MedlinePlus | a619011 |
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Pregnancy category |
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Routes of administration | By mouth |
Drug class | 5-HT4 receptor agonist[1] |
Legal status | |
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Chemical and physical data | |
Formula | C18H26ClN3O3 |
Molar mass | 367.87 g·mol−1 |
3D model (JSmol) | |
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Prucalopride, sold under the brand name Resolor among others, is a medication used to treat chronic constipation of unknown cause.[1][2] It may be used when other laxatives are not effective; though is not recommended in Scotland.[3] It is taken by mouth.[1]
Common side effects include headache, nausea, diarrhea, and abdominal pain.[1] Other side effects may include allergic reactions and suicide.[2] Safety in pregnancy is unclear.[2] It is a 5-HT4 receptor agonist which works by stimulating movement of the gut.[1]
Prucalopride was approved for medical use in Europe in 2009,[1] Canada in 2011,[4] Israel in 2014,[5] and the United States in 2018.[2] In the United Kingdom four weeks of medication costs the NHS about £60 as of 2021.[3] In the United States this amount costs about 430 USD.[6]
References[edit]
- ^ a b c d e f g h i "Resolor". Archived from the original on 31 January 2010. Retrieved 29 October 2021.
- ^ a b c d "Prucalopride Monograph for Professionals". Drugs.com. Archived from the original on 28 January 2021. Retrieved 29 October 2021.
- ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 64. ISBN 978-0857114105.
- ^ "Health Canada, Notice of Decision for Resotran". hc-sc.gc.ca. Archived from the original on 18 March 2017. Retrieved 1 May 2018.
- ^ "Digestive Remedies in Israel". www.euromonitor.com. Archived from the original on 13 March 2018. Retrieved 1 May 2018.
- ^ "Motegrity Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 29 October 2021.