User:Mr. Ibrahem/Rimexolone

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Mr. Ibrahem/Rimexolone
Clinical data
Trade namesVexol
Other namesTrimexolone; Org 6216; 11β-Hydroxy-16α,17α,21-trimethylpregna-1,4-dien-3,20-dione
AHFS/Drugs.comMonograph
MedlinePlusa606003
Routes of
administration
Eye drops
Drug classCorticosteroid
Pharmacokinetic data
Elimination half-lifeestimated 1–2 hours
Excretion>80% faeces
Identifiers
  • (8S,9S,10R,11S,13S,14S,16R,17S)-11-Hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Chemical and physical data
FormulaC24H34O3
Molar mass370.533 g·mol−1
3D model (JSmol)
  • CCC(=O)[C@]1([C@@H](C[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C)C)C
  • InChI=1S/C24H34O3/c1-6-20(27)24(5)14(2)11-18-17-8-7-15-12-16(25)9-10-22(15,3)21(17)19(26)13-23(18,24)4/h9-10,12,14,17-19,21,26H,6-8,11,13H2,1-5H3/t14-,17+,18+,19+,21-,22+,23+,24-/m1/s1 ☒N
  • Key:QTTRZHGPGKRAFB-OOKHYKNYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Rimexolone, sold under the brand name Vexol, is a steroid medication used to treat inflammation of the eye.[1] This includes anterior uveitis and following surgery of the eye.[1] It is used as an eye drop.[1]

Common side effects include increased intraocular pressure, blurry vision, eye pain, redness, and a runny nose.[1] Other complications can include fungal infection of the cornea.[1]

Rimexolone was approved for medical use in the United States in 1994.[1] In the United States a 5 ml bottle costs about 100 USD as of 2021.[2] It is no longer available in the United Kingdom as of 2019.[3]

References[edit]

  1. ^ a b c d e f g h "Rimexolone Monograph for Professionals". Drugs.com. Archived from the original on 20 January 2021. Retrieved 17 October 2021.
  2. ^ "Vexol Prices, Coupons & Patient Assistance Programs". Drugs.com. Retrieved 17 October 2021.
  3. ^ "Rimexolone eye drops. Rimexolone antibiotic eye drops - Patient". patient.info. Archived from the original on 13 August 2021. Retrieved 17 October 2021.