User:Mr. Ibrahem/Uveitis

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Uveitis
Inflammation of the eye and keratic precipitates due to uveitis
Pronunciation
SpecialtyOphthalmology
SymptomsBlurry vision, floaters, eye pain, red eye, sensitivity to light[1]
ComplicationsVision loss, glaucoma[1][2]
Usual onsetSudden[1]
TypesAnterior, intermediate, posterior[1]
CausesInfection: Cytomegalovirus, histoplasmosis, shingles, toxoplasmosis[1]
Autoimmune: Behcet’s disease, psoriasis, ulcerative colitis, lupus[1]
Risk factorsCigarette smoking[1]
Diagnostic methodBased on symptoms and eye exam[1]
Differential diagnosisRetinoblastoma, lymphoma, glaucoma[2]
TreatmentSteroids, atropine, underlying cause[3][2]
PrognosisUsually good with treatment[3]
Frequency1 in 3,000 per year[4]

Uveitis is inflammation inside the eye.[1] Onset is usually sudden.[1] Early symptoms include blurry vision, floaters, eye pain, red eye, and sensitivity to light.[1] One or both eyes may be affected.[1] Complications may include loss of vision and glaucoma.[1][2]

Causes may be unknown, eye infection, or autoimmune conditions.[1][4] Risk factors include cigarette smoking.[1] The uvea is the iris, ciliary body, and choroid.[1] It is divided into anterior, intermediate, and posterior uveitis; though in panuveitis all parts may be affected.[1] Diagnosis is based on symptoms and a dilated eye exam.[1]

Treatment is usually with steroids, most commonly as eye drops such as prednisolone.[1][5] In severe cases steroids by mouth or by injection may be used.[5] If steroids are not effective other immunosuppressants such as methotrexate may be used.[5] Cycloplegics, such as atropine, may be used to help with pain and prevent complications.[3] In cases due to infection, specific treatment for the infection is also required.[2]

Uveitis affects about 1 in 3,000 people per year.[4] It most commonly occurs in those between the ages of 20–60; though any age may be affected.[1] Males and females are affected at similar rates.[4] It accounts for about 5-10% of vision problems globally and is the cause of up to 25% of blindness in the developing world.[4] With appropriate treatment outcomes are usually good.[3]

References[edit]

  1. ^ a b c d e f g h i j k l m n o p q r s t "Uveitis | National Eye Institute". www.nei.nih.gov. Archived from the original on 3 December 2021. Retrieved 21 January 2022.
  2. ^ a b c d e Gueudry, J; Muraine, M (January 2018). "Anterior uveitis". Journal francais d'ophtalmologie. 41 (1): e11–e21. doi:10.1016/j.jfo.2017.11.003. PMID 29290458.
  3. ^ a b c d Duplechain, A; Conrady, CD; Patel, BC; Baker, S (January 2022). "Uveitis". PMID 31082037. {{cite journal}}: Cite journal requires |journal= (help)
  4. ^ a b c d e Tsirouki, T; Dastiridou, A; Symeonidis, C; Tounakaki, O; Brazitikou, I; Kalogeropoulos, C; Androudi, S (2018). "A Focus on the Epidemiology of Uveitis". Ocular immunology and inflammation. 26 (1): 2–16. doi:10.1080/09273948.2016.1196713. PMID 27467180.
  5. ^ a b c Gamalero, L; Simonini, G; Ferrara, G; Polizzi, S; Giani, T; Cimaz, R (July 2019). "Evidence-Based Treatment for Uveitis". The Israel Medical Association journal : IMAJ. 21 (7): 475–479. PMID 31507124.