1550s in architecture

Buildings

 * 1550–1554 – Church of Sant'Andrea in Via Flaminia, Rome, designed by Giacomo Barozzi da Vignola, constructed, the first church of the Italian Renaissance to have an elliptical dome.
 * 1550–1557 – Süleymaniye Mosque in Istanbul, designed by Mimar Sinan, constructed.
 * 1552–1554 – Design and construction of Villa Cornaro in the Veneto by Palladio.
 * 1552 – Work begins on Fort Saint Elmo on Malta.
 * 1554
 * Work begins on Saint Basil's Cathedral in Moscow.
 * Work begins on Sulaymaniyya Takiyya (western building) in Damascus.
 * c. 1555 – Design and construction of monastery of Santiago Apóstol and its basilica church in Cuilapan de Guerrero, Oaxaca, Mexico, by Antonio de Barbosa, begins.
 * 1558 – Sforza Chapel in Basilica di Santa Maria Maggiore, Rome, designed by Michelangelo.
 * 1559
 * Work begins on the Villa Farnese at Caprarola, designed by Vignola.
 * Sulaymaniyya Takiyya (western building) in Damascus is completed.

Births

 * 1550: April 18 – Alessandro Pieroni, Italian mannerist painter and architect (died 1607)
 * c.1550 – Vittorio Cassar, Maltese architect (died c.1607)
 * 1556 – Carlo Maderno, Ticinese-born baroque architect (died 1629)

Deaths

 * 1554 – Sebastiano Serlio (born 1475)