1900 United States presidential election in South Carolina

The 1900 United States presidential election in South Carolina took place on November 6, 1900 as part of the 1900 United States presidential election. Voters chose nine representatives, or electors, to the Electoral College, who voted for the President and Vice President.

South Carolina overwhelmingly voted for the Democratic nominee, former U.S. Representative and 1896 Democratic presidential nominee William Jennings Bryan, over the Republican nominee, President William McKinley. Bryan won South Carolina by a landslide margin of 85.92% in this rematch of the 1896 presidential election. Despite McKinley’s decisive victory nationwide as a result of the return of economic prosperity and recent victory in the Spanish–American War, South Carolina proved to be his weakest state as well as Bryan's strongest state, due to the nearly complete disfranchisement of the black majority that was the party’s sole support in the state.

This would be the last election when the Republican Party won any county in South Carolina until Dwight D. Eisenhower in 1952, and the last when any county voted against the Democrats until Dixiecrat Strom Thurmond carried every county except Anderson and Spartanburg in 1948.

Bryan had previously won South Carolina against McKinley four years earlier and would later win the state again in 1908 against William Howard Taft.