1921–22 Netherlands Football League Championship

The Netherlands Football League Championship 1921–1922 was contested by 43 teams participating in four divisions. The national champion would be determined by a play-off featuring the winners of the eastern, northern, southern and western football division of the Netherlands. Go Ahead won this year's championship by beating Blauw-Wit Amsterdam, NAC, and Be Quick 1887.

New entrants
Eerste Klasse East:
 * Promoted from 2nd Division: Heracles

Eerste Klasse North:
 * Promoted from 2nd Division: Upright

Eerste Klasse South:
 * Promoted from 2nd Division: PSV Eindhoven

Eerste Klasse West:
 * Promoted from 2nd Division: Feijenoord (returning after two seasons of absence) & RCH

Play-off
Go Ahead won the championship.