1945 Tennessee A&I Tigers football team

The 1945 Tennessee A&I Tigers football team represented Tennessee Agricultural & Industrial State College as a member of the Midwest Athletic Association (MAA) during the 1945 college football season. In their second season under head coach Henry Kean, the Tigers compiled a 9–2 record (3–0 against conference opponents), won the MAA championship, defeated Texas College in the Vulcan Bowl, and outscored opponents by a total of 335 to 69. The team played its home games at Tennessee State Stadium and Sulphur Dell in Nashville, Tennessee.