1961 NCAA University Division basketball tournament

The 1961 NCAA University Division basketball tournament involved 24 schools playing in single-elimination play to determine the national champion of men's NCAA Division I college basketball in the United States. It began on March 14, 1961, and ended with the championship game on March 25 in Kansas City, Missouri. A total of 28 games were played, including a third place game in each region and a national third place game.

Cincinnati, coached by Ed Jucker, won the national title with a 70–65 victory in the final game over in-state rival and defending national champion Ohio State, coached by Fred Taylor. Jerry Lucas of Ohio State was named the tournament's Most Outstanding Player.

The national third-place game, won by Saint Joseph's over by the score of 127–120 in four overtimes, tied the record for the longest game in NCAA Division I tournament history, set in 1956 in a first-round game between Canisius and North Carolina State. As of the regional finals of the 2019 tournament, no NCAA Division I tournament games since then have gone to a fourth overtime period. Saint Joseph's victory was later vacated because of the 1961 gambling scandal.

Bracket
* – Denotes overtime period

Final Four
* - denotes overtime

# - Saint Joseph's was later forced to vacate their appearance in the 1961 NCAA Tournament due to a gambling scandal involving a player on the team. Unlike forfeiture, a vacated game does not result in the other school being credited with a win, only with Saint Joseph's removing the wins from its own record.