1964–65 Mexican Segunda División season

The 1964–65 Mexican Segunda División was the 15th season of the Mexican Segunda División. The season started on 6 June 1964 and concluded on 27 December 1964. It was won by Ciudad Madero.

Changes

 * Cruz Azul was promoted to Primera División.
 * Refinería Madero was renamed as Ciudad Madero.
 * Puebla joined the league.
 * Salamanca returned to the league after three seasons on hiatus.
 * The Chapingo Autonomous University became co-owner of the C.D. Texcoco, for which the team was renamed as Chapingo Texcoco.